Title of article :
ZrP2O7 NPs: A recyclable, efficient heterogeneous catalyst for the synthesis of 1,6-diamino-2-oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives via a multi-component reaction
Author/Authors :
Safaei-Ghomi، Javad نويسنده , , Shahbazi-Alavi، Hossein نويسنده Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167, Kashan, I.R. Iran , , Saberi-Moghadam، Mohammad Reza نويسنده Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167, Kashan, I.R. Iran , , Ziarati، Abolfazl نويسنده Department of Organic Chemistry, Faculty of Chemistry, University of Kashan, 51167, Kashan, I.R. Iran ,
Abstract :
ZrP2O7 nanoparticles (NPs) as an efficient catalyst have been used for the preparation of 1,6-diamino-2- oxo-4-phenyl-1,2-dihydropyridine-3,5-dicarbonitrile derivatives via one-pot coupling of hydrazine hydrate, ethyl cyanoacetate, malononitrile and aromatic aldehydes under reflux conditions in ethanol. Using this method we obtained low reaction times, easy isolation of the targeted molecules, excellent yields.
