Author/Authors :
Hashemi، Reza نويسنده Department of Pulmonary Medicine, Shahid Beheshti University of Medical Sciences, Tehran, IR Iran Hashemi, Reza , Majidi، Alireza نويسنده Department of Emergency Medicine, Shohadaye Tajrish Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran , , Tabatabaey، Ali نويسنده Department of emergency medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran , , Motamed، Hassan نويسنده Department of emergency medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran ,
Abstract :
Introduction: Cryptococcosis is an opportunistic fungal infection mostly in immunocompromised patients. Here we present the
immunocompetent case with crypotoccosis. Case Presentation: A 60-year-old man without any history of immunodeficiency or major risk factor of fungal infection, referred to the
emergency department with systemic symptoms and low back pain. The patient’s condition gradually deteriorated within days by forming
the clinical picture of a multi?system disease and eventually leading to a fatal outcome. The results of skin biopsy, BAL, gastrointestinal
biopsy samples and post mortem lung and liver necropsies confirmed the disseminated Cryptococcus neoformans infection in smears and
cultures. Discussion: This case emphasizes the need for a high index of suspicion for fungal infections in patients with multi?organ involvements
who are unresponsive to treatment. Even without any obvious history or sign of immunodeficiency
