Title of article
Xenocladoniamide F, minimal indolotryptoline from the cladoniamide pathway
Author/Authors
Du، نويسنده , , Yi-Ling and Ding، نويسنده , , Tong and Patrick، نويسنده , , Brian O. and Ryan، نويسنده , , Katherine S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
5635
To page
5638
Abstract
The isolation and structure elucidation of indolotryptoline alkaloid xenocladoniamide F (8) from a cladoniamide heterologous production system is reported. The structure of 8 is determined by NMR and X-ray crystallography. Relative to the parent cladoniamides, 8 lacks any remnant of an N-methylsuccinimide ring. This pentacyclic alkaloid is the most minimal indolotryptoline natural product yet reported.
Keywords
Streptomyces , Bisindole alkaloid , heterologous expression , Indolotryptoline
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1886300
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