Title of article
Novel iodine catalyzed diastereoselective synthesis of trans-2,6-disubstituted tetrahydro-2H-pyrans: synthesis of C1–C13 fragment of bistramide-A
Author/Authors
Yadav، نويسنده , , Jhillu Singh and Gyanchander، نويسنده , , Eppa and Mishra، نويسنده , , Anand Kumar and Adithya، نويسنده , , Peddapuram and Das، نويسنده , , Saibal، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
4
From page
5879
To page
5882
Abstract
A new method for the stereoselective synthesis of trans 2.6-disubstituted tetrahydro-2H-pyrans has been developed involving iodine catalyzed allylation of tetrahydro-2H-pyranol with excellent trans selectivity. The method was also applied toward the construction of C1–C13 fragment of bistramide-A in 11 steps with 21.4% overall yield.
Keywords
tetrahydropyrans , Iodine catalyzed allylation , Non Evans aldol , Isomerization , Bistramide A
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1886403
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