Title of article
Additional cytotoxic substances isolated from the sponge-derived Gymnascella dankaliensis
Author/Authors
Amagata، نويسنده , , Taro and Tanaka، نويسنده , , Makoto and Yamada، نويسنده , , Takeshi and Chen، نويسنده , , Yi-Pei and Minoura، نويسنده , , Katsuhiko and Numata، نويسنده , , Atsushi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
5960
To page
5962
Abstract
A continuous investigation of secondary metabolites produced by the sponge-derived fungus, Gymnascella dankaliensis, has yielded a new polyketide tyrosine derivative, dankastatin C (3) and the known steroid, demethylincisterol A3 (4), which was originally found from a Homaxinella marine sponge. The stereostructure of the new compound has been determined based on the analysis of 1D and 2D NMR data. Dankastatin C (3) showed potent cell growth inhibitory activity against the murine P388 cell line.
Keywords
Dankastain , Marine-derived fungi , Cytotoxic secondary metabolites , Gymnascella dankaliensis
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1886442
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