Title of article
ZnO-mediated regioselective C-arylsulfonylation of indoles: a facile solvent-free synthesis of 2- and 3-sulfonylindoles and preliminary evaluation of their activity against drug-resistant mutant HIV-1 reverse transcriptases (RTs)
Author/Authors
Tocco، نويسنده , , Graziella and Begala، نويسنده , , Michela and Esposito، نويسنده , , Francesca and Caboni، نويسنده , , Pierluigi and Cannas، نويسنده , , Valeria and Tramontano، نويسنده , , Enzo، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
5
From page
6237
To page
6241
Abstract
A ZnO-mediated one-pot solvent-free protocol for the regioselective C-arylsulfonylation of indoles is described and some novel derivatives were tested on wild type and non-nucleoside inhibitor resistant K103N and Y181C HIV-1 reverse transcriptases (RTs).
Keywords
regioselectivity , C-Arylfonylation , indoles , non-nucleoside inhibitor , HIV-1 RT
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1886581
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