Title of article
Preyssler catalyst-promoted rapid, clean, and efficient condensation reactions for 3H-1,5-benzodiazepine synthesis in solvent-free conditions
Author/Authors
Pasquale، نويسنده , , Gustavo A. and Ruiz، نويسنده , , Diego M. and Jios، نويسنده , , Jorge L. and Autino، نويسنده , , Juan C. and Romanelli، نويسنده , , Gustavo P.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
6
From page
6574
To page
6579
Abstract
A simple, convenient, and environmentally benign synthesis of 1,5-benzodiazepines is developed by condensing different o-phenylenediamines and 1,3-aryl-1,3-propanodiones. The reaction is catalyzed by a Preyssler (NaH14P5W30O110, HPA) heteropolyacid as a safe, clean, and recyclable catalyst. The method is operationally simple and provides access to a variety of 1,5-benzodiazepines in good to excellent yields.
Keywords
3-propanediones , Preyssler catalyst , solvent-free , 5-benzodiazepines , 3H-1 , 1 , o-phenylenediamine , 3-Diaryl-1
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1886784
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