A new fluorescent double-cavity calix[4]arene: synthesis and complexation studies toward nitroanilines

A novel bicyclic calix[4]arene (4) molecular receptor has been synthesized, and its sensory abilities toward noxious aromatic nitroamines evaluated in apolar media. Molecular host–guest interactions examined through fluorescence and 1H NMR spectroscopies showed the formation of 1:1 type endo-inclusion complexes with all the nitroaniline guests. The potential of 4 as a chemical sensor is established.