Title of article
Iron-catalyzed one-pot synthesis of benzimidazoles from 2-nitroanilines and benzylic alcohols
Author/Authors
Li، نويسنده , , Gang and Wang، نويسنده , , Jin and Yuan، نويسنده , , Baokun and Zhang، نويسنده , , Dongfeng and Lin، نويسنده , , Ziyun and Li، نويسنده , , Peng and Huang، نويسنده , , Haihong، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
6934
To page
6936
Abstract
The iron-catalyzed heterocyclizations from 2-nitroanilines and benzylic alcohols to form benzimidazoles using hydrogen transfer reaction were investigated in this study. In the presence of dppf in toluene at 150 °C, various benzimidazoles were obtained in moderate to good yields within 24 h. The reaction was proposed to proceed via a cascade of alcohol oxidation, nitro reduction, condensation, and dehydrogenation.
Keywords
Benzimidazole , Hydrogen transfer , dppf , one-pot synthesis
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1886969
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