Title of article
A novel and convenient strategy for the synthesis of phthalazines from an aryne precursor
Author/Authors
Bel Abed، نويسنده , , Hassen and Bande، نويسنده , , Omprakash and Mammoliti، نويسنده , , Oscar and Van Lommen، نويسنده , , Guy and Herdewijn، نويسنده , , Piet، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2013
Pages
3
From page
7056
To page
7058
Abstract
A novel three-step entry toward phthalazine derivatives has been elaborated. A strategy based on a sequential acyl-alkylation/diazo transfer reaction/Diaza-Wittig reaction led to the desired analogues in moderate to good yields from an aryne precursor. Various aryl groups were introduced on the annulated pyridazine, moreover the presence of an ester group allows further modifications.
Keywords
Phthalazine , Aryne , Pyridazine , Diaza-Wittig
Journal title
Tetrahedron Letters
Serial Year
2013
Journal title
Tetrahedron Letters
Record number
1887018
Link To Document