Title of article
Synthesis and structural characterization of an anti-inflammatory principle purified from Lindera aggregata
Author/Authors
Kuo، نويسنده , , Ping-Chung and Li، نويسنده , , Yue-Chiun and Hwang، نويسنده , , Tsong-Long and Ma، نويسنده , , Guo-Hao and Yang، نويسنده , , Mei-Lin and Lee، نويسنده , , E-Jian and Wu، نويسنده , , Tian-Shung، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
3
From page
108
To page
110
Abstract
Linderaggrine A (1) was characterized from the roots of Lindera aggregata and its chemical structure was established by the spectral analysis and chemical transformation. The chemical preparation of 1 and its isomer 2 provide unambiguous evidences for the structural determination of the naturally isolated compound. In addition, the inhibition of superoxide anion generation and elastase release by human neutrophils in response to FMLP/cytochalasin B of these synthetic products had been examined and among the tested compounds, linderaggrine A (1) displayed significant potential against the superoxide anion generation.
Keywords
Pictet–Spengler reaction , Lindera , ?-Carboline , Superoxide anion generation , Lauraceae
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1887138
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