Title of article
An Efficient, Three-Component Synthesis of 3,4-Di Hydropyrimidin-2(1H)-Ones Using LaCl3/ClCH2COOH as Environmentally Benign and Green Catalytic System
Author/Authors
Khajesamani، H. نويسنده Department of Chemistry,Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman 76169, Islamic Republic of Iran , , Pouramiri، B. نويسنده Department of Chemistry,Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman 76169, Islamic Republic of Iran , , Tavakolinejad Kermany، E. نويسنده Department of Chemistry,Faculty of Sciences, Shahid Bahonar University of Kerman, Kerman 76169, Islamic Republic of Iran , , Khabazzadeh، H. نويسنده Department of Chemistry, Faculty of Sciences, Shahid Bahonar University of ,
Issue Information
فصلنامه با شماره پیاپی سال 2014
Pages
297
From page
27
To page
323
Abstract
An improved, simple, and facile synthesis of 3,4-dihydropyrimidin-2(1H)-ones by employing three-component, one-pot condensation reaction of B-keto ester, aromatic aldehydes, and urea or N-methylurea using LaCl3/ClCH2COOH as an inexpensive and green chemistry catalyst system under solvent-free conditions described. Compared with the classicalBiginelli reaction conditions, this method has the advantages of good to excellent yields (80-99%) and short reaction time.
Journal title
Journal of Sciences
Serial Year
2014
Journal title
Journal of Sciences
Record number
1887243
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