Title of article
Reductive removal of methoxyacetyl protective group using sodium borohydride
Author/Authors
Gadekar، نويسنده , , Pradip K. and Hoermann، نويسنده , , Maryann and Corbo، نويسنده , , Faith and Sharma، نويسنده , , Rajiv and Sarveswari، نويسنده , , Shashwat S. and Roychowdhury، نويسنده , , Abhijit، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
503
To page
506
Abstract
Herein, we have developed a mild and selective reductive deprotection method for the MAc protected alcohols using sodium borohydride. The new deprotection conditions provide a complete orthogonality between O-MAc and other protecting groups such as tert-butyl ester, N-Boc, Fmoc, Cbz, O-TBDMS, N-benzyl, O-benzyl, O-acetyl, N-acetyl, N-MAc, etc. In addition to O-MAc deprotection, this method is also applicable for S-MAc deprotection.
Keywords
Methoxyacetate , Reductive deprotection , selective , sodium borohydride
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1887664
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