Title of article
Pictet–Spengler reactions of oxetan-3-ones and related heterocycles
Author/Authors
Beasley، نويسنده , , Benjamin O. and Alli-Balogun، نويسنده , , Abimbola and Clarkson، نويسنده , , Guy J. and Shipman، نويسنده , , Michael، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
3
From page
541
To page
543
Abstract
Pictet–Spengler reactions of oxetan-3-ones and azetidin-3-ones with tryptamine and tryptophan derivatives produce spirocyclic tetrahydro-β-carbolines in good yields. Molecular iodine (5 mol %) is an effective catalyst in most cases and high levels of diastereoselectivity are witnessed using 2-substituted oxetan-3-ones.
Keywords
Heterocycles , Oxetanes , imines , Catalysis , spiro compounds
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1887711
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