Title of article :
Generation of 1-(trifluoromethyl)-1,2-dihydroisoquinolines via a silver(I)-catalyzed reaction of 2-alkynylaryl aldimine with trimethyl(trifluoromethyl)silane
Author/Authors :
Wang، نويسنده , , Xianbo and Qiu، نويسنده , , Guanyinsheng and Zhang، نويسنده , , Ling and Wu، نويسنده , , Jie، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
A silver(I)-catalyzed reaction of 2-alkynylaryl aldimine with trimethyl(trifluoromethyl)silane is reported. This reaction proceeds efficiently under extremely mild conditions to generate 1-(trifluoromethyl)-1,2-dihydroisoquinolines in good yields. A three-component reaction of 2-alkynylbenzaldehyde, amine, with trimethyl(trifluoromethyl)silane is presented as well.
Keywords :
2-Alkynylaryl aldimine , Silver hexafluorostiboranuide , Amine , 1-(Trifluoromethyl)-1 , 2-Dihydroisoquinoline , Trimethyl(trifluoromethyl)silane
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
