Title of article
Synthesis of chiral butenolides using amino-thiocarbamate-catalyzed asymmetric bromolactonization
Author/Authors
Tan، نويسنده , , Chong Kiat and Er، نويسنده , , Jun Cheng and Yeung، نويسنده , , Ying-Yeung and Corey، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
1243
To page
1246
Abstract
The asymmetric cyclization of 4,4-disubstituted 3-butenoic acids is studied. Amino-thiocarbamates are used as the catalysts and N-bromosuccinimide is used as the stoichiometric halogen source. The resulting γ-butanolide products are readily converted into the corresponding γ-butenolides (up to 58% ee) derivatives in one-pot.
Keywords
Asymmetric reaction , Lewis base , Catalysis , Bromolactonization
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1888178
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