Title of article
Bifunctional AgOAc/ThioClickFerrophos complex-catalyzed asymmetric 1,3-dipolar cycloaddition of azomethine ylides with aryl- and alkylidene malonates
Author/Authors
Watanabe، نويسنده , , Sayo and Tada، نويسنده , , Atsuo and Tokoro، نويسنده , , Yuichiro and Fukuzawa، نويسنده , , Shin-ichi، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
1306
To page
1309
Abstract
AgOAc/ThioClickFerrophos complex-catalyzed 1,3-dipolar cycloaddition of glycine imino ester, the precursor of azomethine ylide, with aryl- and alkylidene malonates afforded the corresponding exo-cycloadducts, that is, proline ester derivatives in high yields with high enantiomeric excess (up to 99% ee). The reactions proceeded smoothly under base-free conditions demonstrating the bifunctional catalysis of the silver complex.
Keywords
Azomethine ylide , Alkylidene malonate , Chiral phosphine , Ferrocene ligand , cycloaddition
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1888206
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