Title of article
A facile method for the preparation of bishomopropargylic alcohols from acyl chlorides
Author/Authors
Vلsquez، نويسنده , , Suhelen and Cabezas، نويسنده , , Jorge A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
1894
To page
1897
Abstract
Controlled dilithiation of propargyl bromide with two equivalents of n-butyllithium, in the presence of TMEDA, produces the operational equivalent of the dianion 1,3-dilithiopropyne. The latter reacts efficiently with acid chlorides to produce bishomopropargylic alcohols in a single step route and with high regioselectivity and moderate yields.
Keywords
3-dilithiopropyne , homopropargylation , homopropargyl alcohols , Bishomopropargyl alcohols , 1 , Propargyl bromide lithiation
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1888581
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