Title of article :
Facile one-step synthesis of 2,5-diketopiperazines
Author/Authors :
Sun، نويسنده , , Xianyu and Rai، نويسنده , , Rachita and MacKerell Jr.، نويسنده , , Alexander D. and Faden، نويسنده , , Alan I. and Xue، نويسنده , , Fengtian، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
We report a one-step protocol for the general synthesis of 2,5-diketopiperazines from an Fmoc-protected amino acid and an amino acid ester. The application of the method is highlighted by rapid and efficient preparation of various 2,5-diketopiperazines.
Keywords :
Diketopiperazine , Fmoc deprotection , Intramolecular cyclization , Amide formation , neuroprotection
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
