Title of article
Binding of acetylcholine and quaternary ammonium compounds to a C3-symmetric bowl-shaped tripeptide of 2-(3-aminophenoxy)propanoic acids acting as a ditopic receptor
Author/Authors
Akazome، نويسنده , , Motohiro and Hamada، نويسنده , , Norihiro and Takagi، نويسنده , , Koji and Yagyu، نويسنده , , Daisuke and Matsumoto، نويسنده , , Shoji، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
2226
To page
2229
Abstract
The new tripeptide reported here is composed of (R)-2-(3-aminophenoxy)propionic acid and is a bowl-shaped receptor that simultaneously binds both cations and anions of acetylcholine chloride and benzyltrimethylammonium compounds. An intriguing conformational change of the host was observed in the complexation of the ionic pair, where anion-induced flipping of the amide group on the macrocycle occurred.
Keywords
Tripeptide , Bowl-shaped structure , ion-pair recognition , quaternary ammonium compounds
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1888821
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