• Title of article

    Synthesis of maresin 1 and (7S)-isomer

  • Author/Authors

    Ogawa، نويسنده , , Narihito and Tojo، نويسنده , , Toshifumi and Kobayashi، نويسنده , , Yuichi، نويسنده ,

  • Issue Information
    هفته نامه با شماره پیاپی سال 2014
  • Pages
    4
  • From page
    2738
  • To page
    2741
  • Abstract
    Maresin 1 (with the 7R carbon) and (7S)-maresin 1 were synthesized stereoselectively. The conjugated triene system was constructed by Pd-catalyzed coupling of the trans cis-dienylborane (the C10–C22 part) with the trans vinyl iodide corresponding to the C1–C9 part. The stereogenic centers at C7 and C14 were created by Ru-catalyzed asymmetric reduction of ketone and asymmetric epoxidation/kinetic resolution of the racemic alcohol, respectively.
  • Keywords
    Suzuki–Miyaura coupling , lipid mediator , Docosahexaenoic acid , Maresin 1 , stereoselective synthesis
  • Journal title
    Tetrahedron Letters
  • Serial Year
    2014
  • Journal title
    Tetrahedron Letters
  • Record number

    1889210

    • Link To Document
    https://search.isc.ac/dl/search/defaultta.aspx?DTC=10&DC=1889210