Author/Authors :
Xie، نويسنده , , Yong-Sheng and Kumar، نويسنده , , Deepak and Bodduri، نويسنده , , V.D. Vijaykumar and Tarani، نويسنده , , P. Srivastava and Zhao، نويسنده , , Bao-Xiang and Miao، نويسنده , , Jun-Ying and Jang، نويسنده , , Kiwan and Shin، نويسنده , , Dong-Soo، نويسنده ,
Abstract :
A series of benzofuran-2-carboxamides of biological and medicinal significance were synthesized by a microwave-assisted one-pot parallel approach via O-alkylation/Knoevenagel condensation. All the compounds were characterized and assayed for their in vivo anti-inflammatory, analgesic and antipyretic activities. The activity data of all compounds were listed and discussed in detail, among which some derivatives exhibited potent activities of particular interest.
Keywords :
Benzofuran-2-carboxamides , Microwave-assisted synthesis , Knoevenagel condensation , Analgesic Activity , antipyretic activity , anti-inflammatory activity
