Author/Authors :
He، نويسنده , , Jun-Qing and Chen، نويسنده , , Cheng and Yu، نويسنده , , Wu-Bin and Liu، نويسنده , , Ren-Rong and Xu، نويسنده , , Meng and Li، نويسنده , , Yu-Jin and Gao، نويسنده , , Jian-Rong and Jia، نويسنده , , Yi-Xia، نويسنده ,
Abstract :
A nickel-catalyzed intramolecular addition of vinyl or aryl bromides to ketoamides has been developed. The reactions proceeded efficiently with Ni(bpy)Br2 as a catalyst and zinc powder as reducing agent, affording 3-hydroxypyrrolidinones, 3-hydroxyoxindoles, and dihydroquinolinones as important heterocyclic compounds in good to excellent yields.
Keywords :
Bromide , nickel , Addition , Ketoamide , oxindole