Title of article
Synthesis of novel steroids bearing a spirochromene side chain by BF3·Et2O catalyzed aldol condensation of spirostane sapogenins and salicylaldehyde
Author/Authors
Ramos-Enrيquez، نويسنده , , Manuel A. and Iglesias-Arteaga، نويسنده , , Martin A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
3
From page
3325
To page
3327
Abstract
Treatment of a CH2Cl2 solution of sarsasapogenin acetate with salicylaldehyde and BF3·Et2O afforded a mixture of two C-22 epimeric steroids bearing a spirochromene moiety in the side chain. The elucidation of the structures of the new compounds were carried out employing a combination of 1D and 2D NMR techniques that includes 1H, 13C, HSQC, HMBC, COSY and NOESY.
Keywords
Steroid sapogenins , Aldol condensation , NMR , Spirochromene
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1889646
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