Title of article
Total synthesis of agomelatine via Friedel–Crafts acylation followed by Willgerodt–Kindler reaction
Author/Authors
Vujjini، نويسنده , , Satish Kumar and Datla، نويسنده , , V.R. Krishnam Raju and Badarla، نويسنده , , Krishna Rao and Vetukuri، نويسنده , , V.N.K.V. Prasada Raju and Bandichhor، نويسنده , , Rakeshwar and Kagga، نويسنده , , Mukkanti and Cherukupally، نويسنده , , Praveen، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
3
From page
3885
To page
3887
Abstract
Total synthesis of antidepressant drug, agomelatine is reported. Regio selective Friedel–Crafts acylation followed by Willgerodt–Kindler reactions is used as the key steps for the synthesis of agomelatine.
Keywords
Antidepressant drug , Regio selectivity , Agomelatine , Willgerodt–Kindler reaction , Friedel–Crafts acylation
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1889994
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