Title of article
Microwave-assisted α-halogenation of 2-methylquinolines with tetrabutylammonium iodide and 1,2-dichloroethane (1,2-dibromoethane)
Author/Authors
Xie، نويسنده , , Yuanyuan and Li، نويسنده , , Lehuan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
3892
To page
3895
Abstract
A simple and efficient methodology permitting the halogenation of 2-methylquinolines into 2-(chloromethyl)quinolines or 2-(bromomethyl)quinolines in the tetrabutylammonium iodide and 1,2-dichloroethane (1,2-dibromoethane) system has been developed for the first time. The halogenation can be rapidly completed with good to excellent yields and high selectivity under microwave irradiation.
Keywords
Halogenation , tetrabutylammonium iodide , 1 , 2-Methylquinolines , 2-Dichloroethane , microwave
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890001
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