Title of article
A facile synthesis of isoindoline and Δ1-pyrrolines from chalcone and glycine by a cascade of process involving addition, in situ decarboxylation, and cyclization
Author/Authors
Elangovan Elamparuthi، نويسنده , , Elangovan and Sarathkumar، نويسنده , , Subramaniayan and Girija، نويسنده , , Swaminathan and Anbazhagan، نويسنده , , Veerappan، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
3992
To page
3995
Abstract
In this Letter, we report a rapid one-step entry into isoindoline and Δ1-pyrrolines from chalcone. The key step in the synthesis is the addition of glycine to chalcone. In acidic medium the reaction presumably goes through aza-Michael addition, whereas in basic medium the reaction proceeds through condensation followed by cyclization.
Keywords
Isoindoline , ?1-Pyrrolines , aza-Michael addition , Intramolecular electrocyclization , Chalcone
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890071
Link To Document