Title of article :
Stereoselective synthesis of C19–C27 fragment of bryostatin 11
Author/Authors :
Yadav، نويسنده , , J.S. and Swamy، نويسنده , , T. and Subba Reddy، نويسنده , , B.V. and Ravinder، نويسنده , , V.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
A convergent synthesis of C19–C27 fragment (2) of bryostatin-11 is described. The key steps involved in this approach are kinetic resolution, Grignard reaction, and Sharpless dihydroxylation. AIBN catalyzed radical cyclization strategy has been used for the first time to construct the six-membered pyran system.
Keywords :
Sharpless dihydroxylation , radical cyclization , kinetic resolution , Grignard reaction , AIBN
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
