Title of article :
Preparation of 4,5 disubstituted-2H-1,2,3-triazoles from (Z)-2,3-diaryl substituted acrylonitriles
Author/Authors :
Madadi، نويسنده , , Nikhil Reddy and Penthala، نويسنده , , Narsimha Reddy and Song، نويسنده , , Lin and Hendrickson، نويسنده , , Howard P. and Crooks، نويسنده , , Peter A.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
2H-1,2,3-Triazoles (2) were synthesized by [3+2] cycloaddition of (Z)-2,3-diaryl substituted acrylonitriles (1) with sodium azide and ammonium chloride in DMF/water. This method represents a facile and efficient reaction procedure for the synthesis of 4,5-diaryl-2H-1,2,3-triazoles in modest to good yields.
Keywords :
Triazole synthesis , ACRYLONITRILE , Huisgen cycloaddition , sodium azide
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters