Author/Authors :
Hirashima، نويسنده , , Shin-ichi and Sakai، نويسنده , , Takaaki and Nakashima، نويسنده , , Kosuke and Watanabe، نويسنده , , Nana and Koseki، نويسنده , , Yuji and Mukai، نويسنده , , Kanako and Kanada، نويسنده , , Yohei and Tada، نويسنده , , Norihiro and Itoh، نويسنده , , Akichika and Miura، نويسنده , , Tsuyoshi، نويسنده ,
Abstract :
Diaminomethylenemalononitrile organocatalyst 1 efficiently promotes the asymmetric conjugate addition of malonates to α,β-unsaturated ketones to afford the corresponding addition products in high to excellent yields with up to 98% ee.
Keywords :
organocatalyst , Diaminomethylenemalononitrile , Michael addition , solvent-free , Malonate
