Title of article :
One-pot, three component synthesis of novel 5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxylate derivatives by microwave irradiation
Author/Authors :
Zhao، نويسنده , , Bing and Xu، نويسنده , , Yu and Deng، نويسنده , , Qi-Gang and Liu، نويسنده , , Zhuo and Wang، نويسنده , , Li-Yan and Gao، نويسنده , , Yan، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
An efficient one-pot synthetic method for the highly substituted 5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxylate derivatives has been accomplished via a microwave irradiation of MCRs of various aldehydes, 2-aminothiadiazole, and acetoacetate without any catalyst in acetic acid. This approach provides a convenient one pot method for the synthesis of 5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-6-carboxylate derivatives.
Keywords :
5H-1 , 3 , 2-a]pyrimidine-6-carboxylate , microwave irradiation , one-pot synthesis , Three component
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
