Author/Authors :
Ramيrez، نويسنده , , Marيa A. and Ortiz، نويسنده , , Gisela and Levيn، نويسنده , , Gustavo and McCormack، نويسنده , , Walter and Blanco، نويسنده , , Marيa M. and Perillo، نويسنده , , Isabel A. and Salerno، نويسنده , , Alejandra، نويسنده ,
Abstract :
A simple, efficient, and green procedure has been developed for the synthesis of cyclic aminals from alkylenediamines and aqueous formaldehyde under ultrasound irradiation. Applying this methodology a series of five-to eight-membered 1,3-dibenzyl substituted aminals were synthesized in excellent yields after short reaction times. Results were compared to thermal conventional method. All novel compounds were identified and characterized by 1H and 13C NMR spectra.
Keywords :
Alkylenediamines , Cyclic aminals , Ultrasonic assisted synthesis , green chemistry
