Title of article
Highly selective synthesis of 1-polyfluoroaryl-1,2,3-triazoles via a one-pot three-component reaction
Author/Authors
Cao، نويسنده , , Liming and Liu، نويسنده , , Cuibo and Tang، نويسنده , , Xiangyang and Yin، نويسنده , , Xuguang and Zhang، نويسنده , , Bin، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
5
From page
5033
To page
5037
Abstract
A series of 1-polyfluoroaryl-1,2,3-triazoles were synthesized in moderate to good yields by an efficient copper-catalyzed one-pot three-component reaction of polyfluoroarenes, sodium azide, and terminal alkynes. The method involves a polyfluoroarylated azide intermediate produced in situ by the selective CF bond cleavage of polyfluoroarene with sodium azide.
Keywords
1 , 2 , CF cleavage , 4-Disubstituted 1 , Polyfluoroarenes , cycloaddition , 3-Triazoles , multicomponent reactions
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890566
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