Title of article
Facile four-component domino reactions for the synthesis of 2,6-diaryl-4-(1H-indol-3-yl)-3-cyanopyridines
Author/Authors
Bharkavi، نويسنده , , Chelliah and Gunasekaran، نويسنده , , Pethaiah and Vivek Kumar، نويسنده , , Sundaravel and Sakthi، نويسنده , , Marimuthu Venkatesh Perumal، نويسنده , , Subbu، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
5
From page
5486
To page
5490
Abstract
A series of novel 2,6-diaryl-4-(1H-indol-3-yl)-3-cyanopyridines was obtained in good yields from the domino reactions of 3-(1H-indol-3-yl)-3-oxopropanenitrile, 4,4,4-trifluoro-1-phenylbutane-1,3-dione, and aromatic aldehydes in the presence of ammonium acetate under solvent-free condition. This transformation involves the formation of two CC and two CN bonds leading to the creation of a six-membered ring in a one-pot operation.
Keywords
3-Aryl-3-oxopropanenitrile , 4 , 3-dione , Ammonium acetate , Indolylpyridines , 4 , 4-Trifluoro-1-arylbutane-1 , Four-component
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890797
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