Title of article
Rapid synthesis of 1,7-bis(t-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane (DO2A-t-Bu ester)
Author/Authors
Hopper، نويسنده , , Lauren E. and Allen، نويسنده , , Matthew J.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
2
From page
5560
To page
5561
Abstract
A three-step route was used to synthesize 1,7-bis(t-butoxycarbonylmethyl)-1,4,7,10-tetraazacyclododecane (DO2A-t-Bu ester) from 1,4,7,10-tetraazacyclododecane (cyclen). The overall time of reaction was reduced from a combined ∼56 h to 2.3 h with an overall yield comparable to previously reported methods.
Keywords
Cyclen , DO2A-t-Bu ester , Transfer hydrogenation , microwave
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890825
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