Title of article :
Synthesis of N-alkyl-N′-aryl-piperazines via copper-catalyzed C–N bond formation
Author/Authors :
Yavari، نويسنده , , Issa and Bayat، نويسنده , , Mohammad J. and Ghazanfarpour-Darjani، نويسنده , , Majid، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
An efficient copper-catalyzed tandem synthesis of N-alkyl-N′-aryl-piperazines from 1,4-diaza-bicyclo[2.2.2]octane, alkyl halides, and aryl halides in the presence of copper(I) iodide and potassium tert-butoxide in DMSO is described.
Keywords :
Dabco , Copper(I) iodide , C–N cross-coupling , Aryl halide , Alkyl halide , N-Alkyl-N?-aryl-piperazines
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
