Title of article
Chromeno[2,3-c]pyrroles by one-pot multicomponent domino addition–amination reaction
Author/Authors
Terzidis، نويسنده , , Michael A. and Tsiaras، نويسنده , , Vassilios G. and Drosos، نويسنده , , Nicolaos M. and Kasapidou، نويسنده , , Paraskevi M. and Stephanidou-Stephanatou، نويسنده , , Julia and Tsoleridis، نويسنده , , Constantinos A. and Buth، نويسنده , , Gernot and Kostakis، نويسنده , , George E.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
5601
To page
5604
Abstract
A new aspect concerning chromone chemistry leading to the one-pot synthesis of chromeno[2,3-c]pyrroles is described. The synthesis involves a multicomponent reaction of 3-formylchromones with isocyanides and azodicarboxylates, whereupon novel chromeno[2,3-c]pyrrole derivatives were formed in good yields. The structures of the products were elucidated by 1D and 2D NMR experiments and were unambiguously confirmed by the use of crystal X-ray diffraction analysis. Full assignment of all 1H and 13C NMR chemical shifts has been achieved. A plausible mechanistic scheme is proposed.
Keywords
Azodicarboxylates , 3-c]pyrroles , Formylchromones , Isocyanides , multicomponent reactions
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890841
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