Title of article
A facile route for the synthesis of novel S-linked 1,3,5-triazine tethered peptidomimetics
Author/Authors
Krishnamurthy، نويسنده , , Muniyappa and Basavaprabhu and Sharanabai، نويسنده , , K.M. and Sureshbabu، نويسنده , , Vommina V.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
5609
To page
5612
Abstract
An efficient one-pot synthesis of Nα-protected S-linked 1,3,5-triazine tethered peptidomimetics is described. The protocol involves a three-component condensation reaction employing Nα-protected amino alkyl isothiouronium salt, formaldehyde and amino acid ester or aryl amine as reactants. Various aryl amines with substitutions and amino acids with simple as well as bifunctional side chains were employed to obtain triazine tethered peptidomimetics in good yield.
Keywords
Dehydrocyclization , N?-protected amino alkyl isothiouronium salts , Amino acid ester , Formaldehyde
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890844
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