Title of article
A new approach to the synthesis of cross-conjugated cyclopentenone prostaglandins. Synthesis of (±)-15-deoxy-Δ12,14-prostaglandin J2 methyl ester
Author/Authors
Vostrikov، نويسنده , , N.S. and Lobko، نويسنده , , I.F. and Miftakhov، نويسنده , , M.S.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
3
From page
5622
To page
5624
Abstract
A new approach to 15-deoxy-Δ12,14-prostaglandin J2 and related structures based on the (±)-Corey lactone diol has been developed. The key stage of this approach involves building the structure of a prostaglandin (PG) derivative with leaving groups at positions 9, 13, and 15, followed by elimination of these groups by treatment with an organic base.
Keywords
15-Deoxy-?12 , Corey lactone , total synthesis , 14-PGJ2 methyl ester , Cyclopentenone prostaglandins
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890848
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