Title of article
A new route to the versatile synthesis of thiopyrano[2,3-b:6,5-b′]diindoles via 2-(alkylthio)-indole-3-carbaldehydes
Author/Authors
Jha، نويسنده , , Mukund and Edmunds، نويسنده , , Michael T. Lund، نويسنده , , Kate-lyn and Ryan، نويسنده , , Ashley، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
5691
To page
5694
Abstract
A versatile synthesis of symmetrically and unsymmetrically substituted thiopyrano[2,3-b:6,5-b′]diindoles has been developed by the condensation of 2-(alkylthio)-indole-3-carbaldehydes with indoline-2-thiones in the presence of catalytic amount of ethylenediamine diacetate (EDDA). The EDDA mediated condensation leads to a spontaneous cyclization followed by aromatization to form thiopyrano[2,3-b:6,5-b′]diindoles in quantitative yields.
Keywords
cyclization , Sulfide , indole , Heteroaromatic , Formylation
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890883
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