Title of article
Solid-phase synthesis of benzazoles, quinazolines, and quinazolinones using an alkoxyamine linker
Author/Authors
Yamaguchi، نويسنده , , Kota and Noda، نويسنده , , Takeshi and Higuchi، نويسنده , , Yusuke and Aoki، نويسنده , , Naoyuki and Yamaguchi، نويسنده , , Rika and Kubo، نويسنده , , Miwa and Harada، نويسنده , , Kenichi and Fukuyama، نويسنده , , Yoshiyasu and Hioki، نويسنده , , Hideaki، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
5
From page
5793
To page
5797
Abstract
An alkoxyamine linker was applied for the solid-phase synthesis of benzazoles, quinazolines, and quinazolinones. Aromatic aldehydes were anchored by aldoxime linkage. After some reactions on a solid support, the products were cleaved with paraformaldehyde under the acidic conditions to afford the corresponding aldehydes, which were subsequently subjected to oxidative coupling with 2-substituted anilines under air atmosphere to give the desired compounds.
Keywords
Benzimidazole , quinazoline , Quinazolinone , Alkoxyamine linker , solid-phase synthesis
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890929
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