Title of article
Microwave-assisted chemoselective synthesis of novel pyrazolo[3,4-b]thieno[3,4-e]pyridines: substitution induced axial chirality
Author/Authors
Rani، نويسنده , , Mani Anusha and Jeyachandran، نويسنده , , Veerappan and Muthu، نويسنده , , Muthumani and Sivakolunthu، نويسنده , , Subbiah and Kumar، نويسنده , , Raju Ranjith Kumar، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
3
From page
5805
To page
5807
Abstract
A microwave-assisted chemoselective synthesis of novel pyrazolo[3,4-b]thieno[3,4-e]pyridines has been achieved via tandem Michael addition–cyclization–tautomerization–oxidative aromatization sequence of reactions. Compounds with ortho-substituted phenyl rings exhibited axial chirality due to restricted rotation around C–C single bond.
Keywords
4-e]pyridine , axial chirality , Tandem reaction , microwave irradiation , Chemoselective Michael addition
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1890934
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