Author/Authors :
Li، نويسنده , , Liang-Qun and Li، نويسنده , , Mingming and Chen، نويسنده , , Dong and Liu، نويسنده , , Hao-Miao and Geng، نويسنده , , Hui Chun and Lin، نويسنده , , Jun and Qin، نويسنده , , Hong-Bo، نويسنده ,
Abstract :
Catalytic asymmetric formal total synthesis of (+)-dichroanone and (+)-taiwaniaquinone H has been achieved. Key step involved construction of all-carbon quaternary carbon by palladium-catalyzed conjugate addition of arylboronic acid to 3-methyl cyclohexenone. Furthermore, a new approach to build [6-5-6] tricyclic backbone via formyl introduction and subsequent aldol-type condensation was also explored.
Keywords :
(+)-Dichroanone , conjugate addition , Stereoselective formal synthesis , Reetz reagent , (+)-Taiwaniaquinone H
