Title of article
Efficient synthesis and antioxidant activity of coelenterazine analogues
Author/Authors
Lu، نويسنده , , Yueting and Hendra، نويسنده , , Rudi and Oakley، نويسنده , , Aaron J. and Keller، نويسنده , , Paul A.، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
6212
To page
6215
Abstract
A convenient and highly convergent method for the synthesis of new imidazo[1,2-a]pyridine-based coelenterazine analogues is reported. The imidazo[1,2-a]pyridine core was constructed through a condensation between 2-aminopyridine analogues and arylglyoxals. Additionally, a new approach to the synthesis of benzylglyoxals was introduced. The imidazo[1,2-a]pyridines display moderate antioxidant activities at a low micromolar level in 2,2-diphenyl-1-picrylhydrazyl (DPPH).
Keywords
2-Diphenyl-1-picrylhydrazyl , Coelenterazine , 2-a]pyridine , Benzylglyoxals , antioxidant , 2
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1891132
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