Title of article :
Temperature dependent selective synthesis of linear 2-bromo and 2-alkoxyfuro[2,3-b]quinolines: reaction of 3-(2,2-dibromovinyl-)quinolin-2(1H)-ones with alcoholic KOH
Author/Authors :
Nandini، نويسنده , , Durgesh and Asthana، نويسنده , , Mrityunjaya and Mishra، نويسنده , , Kalpana and Singh، نويسنده , , R.P. and Singh، نويسنده , , Radhey M.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
Base promoted and temperature dependent reactions of 3-(2,2-dibromovinyl)quinolin-2(1H)-ones have been described. At 50 °C, the cyclization reactions afforded 2-bromofuro[2,3-b]quinolines in good yields. However, at elevated temperature (80 °C) the domino reaction proceeded affording 2-alkoxyfuro[2,3-b]quinolines via cyclization and nucleophilic substitution reactions.
Keywords :
3-b]quinolines , temperature dependent , 2-Chloro-3-(2 , 3-(2 , Alcoholic KOH , 3-b]quinolines , 2-dibromovinyl)quinoline , 2-Dibromovinyl)quinolin-2(1H)-ones
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
