Title of article
Convenient synthesis of N1-substituted orotic acid derivatives
Author/Authors
Bowler، نويسنده , , Jeannette T. and Clausen، نويسنده , , Caitlin R. and Blackburn، نويسنده , , Daniel J. and Wu، نويسنده , , Weiming، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
2
From page
6465
To page
6466
Abstract
A convenient and efficient method for the synthesis of N1-substituted orotic acid derivatives is reported. The synthetic route utilizes substituted maleimide as synthetic intermediate and takes only four simple steps from readily available starting materials. As a result, orotic acid derivatives with various alkyl and aromatic groups at N1 can be readily synthesized.
Keywords
orotic acid , Orotidine , Synthesis , maleimide , Bromomaleimide , Dibromosuccinimide
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1891249
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