Title of article
Highly unsaturated pyranone derivatives from the basidiomycete Junghuhnianitida
Author/Authors
Hu، نويسنده , , Dong-Bao and Li، نويسنده , , Wen-Xin and Zhao، نويسنده , , Zhen-Zhu and Feng، نويسنده , , Tao and Yin، نويسنده , , Ronghua and Li، نويسنده , , Zheng-Hui and Liu، نويسنده , , Ji-Kai and Zhu، نويسنده , , Hua-Jie، نويسنده ,
Issue Information
هفته نامه با شماره پیاپی سال 2014
Pages
4
From page
6530
To page
6533
Abstract
Four new highly unsaturated pyranone derivatives A–D (1–4), together with one known compound 5 (−)-nitidon were isolated from cultures of the fungus Junghuhnianitida. Planar structures of the new compounds were elucidated on the basis of extensive NMR spectroscopic and mass spectrometric analyses. Absolute configurations of the new compounds were determined on the basis of biosynthetic considerations and quantum chemistry theory. Compound 1 exhibited almost the same cytotoxic activities as cis-platin.
Keywords
DFT , matrix , antitumour agents , Junghuhnianitida derivatives , absolute configuration determination
Journal title
Tetrahedron Letters
Serial Year
2014
Journal title
Tetrahedron Letters
Record number
1891279
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