Author/Authors :
Kawaguchi، نويسنده , , Shin-ichi and Gonda، نويسنده , , Yuhei and Masuno، نويسنده , , Haruna and V?، نويسنده , , Hu? Th? and Yamaguchi، نويسنده , , Kotaro and Shinohara، نويسنده , , Hiroyuki and Sonoda، نويسنده , , Motohiro and Ogawa، نويسنده , , Akiya، نويسنده ,
Abstract :
A facile hydroiodination of alkynes using readily-available reagents such as I2, PPh3, and H2O has been developed. This is extended to the one-pot synthesis of trisubstituted alkenes from alkynes via iodoalkenes using Pd-catalyzed cross-coupling and related methods such as the Suzuki–Miyaura cross-coupling, Sonogashira cross-coupling reaction, and Mizoroki–Heck reaction.
Keywords :
one-pot synthesis , Hydroiodination , trisubstituted alkenes , Phosphorus reagents , Cross-coupling reactions
