Title of article :
Catalyst-free synthesis of (E)-2-alkenylquinoline derivatives via C(sp3)-H functionalization of 2-methylquinolines
Author/Authors :
Xu، نويسنده , , Lubin and Shao، نويسنده , , Zhuzhou and Wang، نويسنده , , Liang and Zhao، نويسنده , , Huaili and Xiao، نويسنده , , Jian، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
This Letter described a facile approach to synthesize (E)-2-alkenylquinoline derivatives via C(sp3)-H functionalization of 2-methylquinolines under catalyst-free conditions. A variety of electronically and sterically diverse 2-methyl quinoline and aromatic aldehydes were well tolerated.
Keywords :
catalyst-free , Olefination , C(sp3)-H activation , 2-Alkenylquinoline , 2-methylquinoline
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters