Title of article :
Acid- and isobutylene-free synthesis of t-butyl ethers by in situ formation of 2-t-butoxy-1-methylpyridinium triflate
Author/Authors :
Salvati، نويسنده , , Anna E. and Hubley، نويسنده , , Christian T. and Albiniak، نويسنده , , Philip A.، نويسنده ,
Issue Information :
هفته نامه با شماره پیاپی سال 2014
Abstract :
The title reagent is formed in situ by alkylation of 2-t-butoxypyrine. The subsequent addition of an alcohol substrate leads to the formation of t-butyl ethers without the need for isobutylene gas or acid activators.
Keywords :
etherification , protecting groups , nucleophilic substitution , Carbocation intermediate , Oxypyridinium salt
Journal title :
Tetrahedron Letters
Journal title :
Tetrahedron Letters
